Many Tsamai use the Konso language for trade purposes.
Most Tsamai live in the Hamer Bena woreda of the Debub Omo Zone of the Southern Nations, Nationalities, and People's Region, in the Lower Omo River Valley and just to the west of the Konso special woreda. Many Tsamai live in the town of Weyto, which is approximately 50 km from the town of Jinka, on the Konso-Jinka road. Most Tsamai are agro-pastoralists, herding cattle as well as growing crops. Many Tsamai women wear clothing made from leather. Many Tsamai men carry small stools around with them, which they use in case they need to sit down.